Using Pydantic with Gemini 2.5 Flash Preview 09-2025 on OpenRouter
This tutorial explains how to use a Pydantic schema to extract structured data using Gemini 2.5 Flash Preview 09-2025.
Please read this tutorial first to understand the basic setup
Code:
import os
import json
import requests
import datetime
from inputs import get_input_text
from system import system_instruction_1 as system_instruction
from schema import VAERSReport
from dotenv import load_dotenv
import time
load_dotenv()
model_name = 'google/gemini-2.5-flash-preview-09-2025'
api_key = os.getenv("OPENROUTER_API_KEY")
json_schema_text = json.dumps(VAERSReport.model_json_schema(), indent=2)
input_text, sentence_map = get_input_text()
prompt = f"""
Report: {input_text}
JSON Schema:
{json_schema_text}
"""
url = "https://openrouter.ai/api/v1/chat/completions"
headers = {
"Authorization": f"Bearer {api_key}",
"Content-Type": "application/json",
"HTTP-Referer": "https://botflo.com/", # Optional. Site URL for rankings on openrouter.ai.
"X-Title": "LLM Accuracy Comparisons for Structured Outputs", # Optional
}
payload = {
"model": model_name,
"messages": [
{"role": "system", "content": f'{system_instruction}'},
{"role": "user", "content": f'{prompt}'}
],
"reasoning": {
"effort": "high"
}
}
before = time.time()
response_full = requests.post(url, headers=headers, data=json.dumps(payload))
elapsed = time.time() - before
response = response_full.json()
metadata = {
"metrics": {
"elapsed": elapsed,
"usage": response['usage']
},
"text": {
"system_instruction": system_instruction,
"sentence_map": sentence_map,
"json_schema_text": json_schema_text
}
}
response["metadata"] = metadata
response_file_name = f"responses/response_{model_name.replace('/', '-')}.json"
with open(response_file_name, 'w+') as f:
json.dump(response, f, indent=2)
output_text = response.get('choices')[0].get('message').get('content')
print(output_text)
input_file_name = f"inputs/input_{model_name.replace('/', '-')}.txt"
with open(input_file_name, 'w+') as f:
f.write(input_text)
output_file_name = f"outputs/output_{model_name.replace('/', '-')}.txt"
with open(output_file_name, 'w+') as f:
f.write(output_text)LLM Response:
```json
{
"timeline": {
"date_of_vaccination": {
"year": 1999,
"month": 6,
"citations": [
3
],
"explanation": null
},
"regression_onset_date": {
"year": 2000,
"month": 10,
"citations": [
147
],
"explanation": "Symptoms of developmental delay and autism began between 21-23 months. Calculation based on 22 months estimated using narrative timeline."
},
"diagnosis_date": {
"year": 2001,
"month": 1,
"citations": [
98,
150
],
"explanation": "Evaluation at the autism resource center occurred on 1/4/01, where PDD could not be ruled out, and the diagnosis of autism was reported as 'recent' in Feb 2001."
},
"age_at_vaccination_months": {
"value": 15.96,
"citations": [
3
],
"explanation": "Reported age is 1.33 years (1.33 * 12 = 15.96 months)."
},
"age_at_diagnosis_months": {
"value": 25,
"citations": [
61,
98
],
"explanation": "The subject was 20 months on 8/22/00 [61]; the primary diagnostic evaluation occurred on 1/4/01, approximately 25 months later."
}
},
"developmental_milestones": [
{
"milestone_name": {
"value": "sitting_without_support",
"citations": [
41
],
"explanation": null
},
"milestone_type": "adaptive_behavior",
"milestone_age_in_months": {
"value": 8,
"citations": [
41
],
"explanation": "Sat w/out support at 8 mts (or 6 months adjusted for prematurity)."
},
"milestone_has_regressed": {
"value": false,
"citations": [
40
],
"explanation": "Motor milestones were delayed, but not reported lost."
},
"regression_start_date_in_months": {
"value": 0,
"citations": null,
"explanation": null
},
"progressed_after_regression": {
"value": false,
"citations": null,
"explanation": null
}
},
{
"milestone_name": {
"value": "walking",
"citations": [
41
],
"explanation": null
},
"milestone_type": "adaptive_behavior",
"milestone_age_in_months": {
"value": 12,
"citations": [
41
],
"explanation": "Walked by 12 mts (or 10 months adjusted for prematurity)."
},
"milestone_has_regressed": {
"value": false,
"citations": null,
"explanation": null
},
"regression_start_date_in_months": {
"value": 0,
"citations": null,
"explanation": null
},
"progressed_after_regression": {
"value": false,
"citations": null,
"explanation": null
}
},
{
"milestone_name": {
"value": "single_words",
"citations": [
41
],
"explanation": null
},
"milestone_type": "language",
"milestone_age_in_months": {
"value": 17,
"citations": [
41
],
"explanation": "Started saying a few single words at around age 17 mts."
},
"milestone_has_regressed": {
"value": true,
"citations": [
147,
115
],
"explanation": "Symptoms began 21-23 months, and the child lost flexible phrase speech and rarely used speech without prompting."
},
"regression_start_date_in_months": {
"value": 22,
"citations": [
147
],
"explanation": "Symptoms of developmental delay and autism began between 21-23 mts."
},
"progressed_after_regression": {
"value": false,
"citations": null,
"explanation": "Autism persisted as of the last update."
}
},
{
"milestone_name": {
"value": "pretend_play",
"citations": [
121,
123
],
"explanation": null
},
"milestone_type": "social_communication",
"milestone_age_in_months": {
"value": null,
"citations": [
121
],
"explanation": "Demonstrated some beginning pretend play skills prior to the recently noted decrease in this type of play."
},
"milestone_has_regressed": {
"value": true,
"citations": [
123
],
"explanation": "Type of play has decreased significantly in the past several wks (reported Jan 2001)."
},
"regression_start_date_in_months": {
"value": 25,
"citations": [
123
],
"explanation": "Loss was reported as happening 'in the past several wks' relative to the 1/4/01 evaluation (~25 months)."
},
"progressed_after_regression": {
"value": false,
"citations": null,
"explanation": "Autism persisted as of the last update."
}
}
],
"regression_record": {
"pre_regression_language_level": {
"value": "babbling_single_words",
"citations": [
41,
62
],
"explanation": "Child started single words at 17 months and was assessed at a 13-15 month language level at 20 months, prior to the major symptomatic onset at 21-23 months."
},
"pre_regression_social_communication_level": {
"value": "reciprocal_interaction",
"citations": [
62
],
"explanation": "Social development level was assessed at 18-20 months at 20 months of age, suggesting approaching age-appropriate interaction."
},
"pre_regression_adaptive_behavior_level": {
"value": "moderate_independence",
"citations": [
41,
75
],
"explanation": "Gross motor was age equivalent (walking achieved at 12 months)."
},
"post_regression_language_level": {
"value": "babbling_single_words",
"citations": [
83,
84,
128
],
"explanation": "Post-regression (25 months), language comprehension and expression were assessed at a 15-month level, characterized by grunting and occasional single words."
},
"post_regression_social_communication_level": {
"value": "basic_engagement",
"citations": [
110,
128
],
"explanation": "Parents noted a decrease in good social behaviors (joint attention, gestures), with socialization age assessed around 14 months at 25 months old."
},
"post_regression_adaptive_behavior_level": {
"value": "moderate_independence",
"citations": [
128,
140
],
"explanation": "Daily living skills were assessed at 15 months (at 25 months old), indicating stagnation or delay, not evident loss of previously acquired concrete adaptive skills."
},
"has_language_loss": {
"value": true,
"citations": [
99,
115,
147
],
"explanation": "Symptoms developed 21-23 months, and flexible phrase speech was lost/not achieved."
},
"has_social_loss": {
"value": true,
"citations": [
110,
111,
123
],
"explanation": "Parents reported decrease in frequency of joint attention/gestures and loss of complex play."
},
"has_adaptive_loss": {
"value": false,
"citations": [
140
],
"explanation": "Adaptive behaviors were noted as below average or delayed (stagnation), but acute loss of motor/self-care skills was not prominent."
},
"has_repetitive_behaviors": {
"value": true,
"citations": [
126,
148
],
"explanation": "Began demonstrating new behaviors such as lining up toys and objects, and used language repetitively."
}
},
"early_vaccination_symptoms": {
"had_autism_features": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": "Autism symptoms began several months later (21-23 months of age)."
},
"had_fever": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_speech_loss": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_irritability": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_eye_contact_loss": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_diarrhea": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_seizures": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_lethargy": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_screaming": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_behavioral_changes": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_rash": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null
},
"had_head_banging": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_social_withdrawal": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_injection_site_reaction": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_balance_loss": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_appetite_loss": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_staring_spells": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_hand_flapping": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_toe_walking": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_gastrointestinal_problems": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_hyperactivity": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_ear_infections": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": "Otitis media occurred at 9 months of age, which is outside the acute 30-day window following the vaccination on 6/30/99 (when the child was 16 months old by VAERS data)."
},
"had_vomiting": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_sleep_problems": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
},
"had_encephalopathy": {
"value": false,
"ongoing": false,
"days_to_symptom_onset": null,
"citations": null,
"explanation": null
}
},
"diagnosis_record": {
"asd_severity": {
"value": 2,
"citations": [
151,
153
],
"explanation": "Rated in the 'moderate' autism category, though symptoms were described as 'mild' but interfering with learning."
},
"diagnosis_name": [
{
"value": "Autism",
"citations": [
21,
45,
150
],
"explanation": null
},
{
"value": "Mixed Expressive Receptive Language Disorder",
"citations": [
96,
130
],
"explanation": null
}
],
"diagnosing_professional": [
{
"value": "Psychologist/Autism Resource Center Staff",
"citations": [
98,
150
],
"explanation": "Diagnosed by the autism resource center."
}
]
},
"intervention_record": {
"interventions": [
{
"value": "speech_therapy",
"citations": [
76,
97,
154
],
"explanation": null
},
{
"value": "occupational_therapy",
"citations": [
143,
154
],
"explanation": null
},
{
"value": "aba",
"citations": [
154
],
"explanation": "Recommended intensive early intervention using applied behavioral analysis (ABA)."
},
{
"value": "other",
"citations": [
79,
97
],
"explanation": "Special instruction was recommended."
}
],
"is_intervention_ongoing": {
"value": true,
"citations": [
154
],
"explanation": "Continued therapies were recommended."
},
"has_recovery": {
"value": false,
"citations": [
11,
162
],
"explanation": "Autism persisted as of 15July02."
}
},
"birth_record": {
"was_normal_pre_vaccination": {
"value": false,
"citations": [
16,
24,
40
],
"explanation": "Child was premature (31.5 wks), had existing conditions (apnea, bradycardia), and motor milestones were noted as not w/in normal limits."
},
"apgar_score": [
{
"value": "8",
"citations": [
29
],
"explanation": "At one minute"
},
{
"value": "9",
"citations": [
29
],
"explanation": "At five minutes"
}
]
},
"behavior_record": {
"repetitive_behaviors": [
{
"value": "Lining up toys and objects (e.g., blocks, chairs)",
"citations": [
126
],
"explanation": "A new behavior reported to have begun recently prior to 1/4/01."
},
{
"value": "Repetitive use of language",
"citations": [
148
],
"explanation": "Symptom listed as observed alongside developmental delay."
}
]
},
"heavy_metal_tests": [
{
"metal_type": "lead",
"value": 16.0,
"unit": "ug/L",
"is_elevated": false,
"citations": [
20
],
"explanation": "Absolute concentration was within reference range (0-79)."
},
{
"metal_type": "arsenic",
"value": 60.0,
"unit": "ug/L",
"is_elevated": false,
"citations": [
20
],
"explanation": "Absolute concentration was within reference range (0-99)."
},
{
"metal_type": "mercury",
"value": 10.0,
"unit": "ug/L",
"is_elevated": false,
"citations": [
20
],
"explanation": "Value was reported as 'less than 10ug/L', which is within the reference range (0-19.9). Using 10.0 as approximate upper bound."
}
],
"comorbidities": [
{
"value": "asthma",
"citations": [
155
],
"explanation": "Diagnosed with reactive airway disease post-regression."
},
{
"value": "other",
"citations": [
16,
135
],
"explanation": "Repeated ear infections (Otitis media)."
},
{
"value": "other",
"citations": [
155
],
"explanation": "Pneumonia."
}
],
"environmental_exposures": [],
"legal_matter": {
"value": true,
"citations": [
22
],
"explanation": "This report was received as part of litigation proceedings."
},
"diagnosis_reporting_delay_reason": null
}
```Metrics
{
"elapsed": 69.27981805801392,
"usage": {
"prompt_tokens": 15225,
"completion_tokens": 18324,
"total_tokens": 33549,
"prompt_tokens_details": {
"cached_tokens": 0
},
"completion_tokens_details": {
"reasoning_tokens": 13294,
"image_tokens": 0
}
}
}